Is Valproic Acid a Treatment for Retinitis Pigmentosa?

November 16, 2010

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Dr. Ari Weitzner

Valproic acid, used for seizures, was shown to improve visual fields in retinitis pigmentosa (RP) patients in a small study. Consider using it off-label until larger prospective studies are done, as it seems to be well-tolerated, and RP patients want options.

 

 

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3 Responses to “Is Valproic Acid a Treatment for Retinitis Pigmentosa?”

  • Dr. Ari Weitzner
    on August 16, 2011 1:56 am

    Here’s information concerning an ongoing clinical trial to evaluate the efficacy of Valproic Acid (VPA) to both slow the progression of visual function loss and/or to restore visual function in patients with Autosomal Dominant Retinitis Pigmentosa (RP) and to collect safety and tolerability information:

    http://www.clinicaltrials.gov/ct2/show/NCT01233609?recr=Open&no_unk=Y&cond=%22Retinitis+Pigmentosa%22&rank=2

  • I.PRASHANT
    on December 1, 2010 7:06 am

    i am suffering from retinitis pigmentosa – i lost 60% of vision.I am happy to hear about Valproic Acid i am searching for latest news daily.

  • Pankaj
    on November 17, 2010 5:42 am

    This news I heard before few months. Such good reasearch but no further updates available regarding clinical trials and treatments etc.