Will Microplasmin Injections Transform Treatment of Vitreomacular Adhesion (Traction) and Macular Hole?
October 9, 2010
Last month, ThromboGenics NV presented the results from the successful microplasmin MIVI-TRUST Phase III program at the EURETINA (European Society of Retina Specialists) Congress in Paris, France (MIVI-TRUST is short for “Microplasmin for IntraVitreous Injection-Traction Release without Surgical Treatment”).
The MIVI-TRUST program is the largest interventional clinical program ever performed to specifically evaluate the vitreoretinal interface in patients with retinal disorders, involving a total of 652 patients at 90 centers across the U.S. and Europe.
The results showed the potential of microplasmin injections to transform the treatment of a range of retinal disorders. Specifically, the Phase III program showed that microplasmin injections:
- Were successful in resolving vitreomacular adhesion (VMA) (also known as vitreomacular traction)
- Were able to cure full thickness macular hole (FTMH) without the need for surgery
- Delivered an improvement in the vision of patients without the need for surgery
- Were safe and well tolerated; there was no evidence of an increased risk of retinal tear or detachment
Read the full ThromboGenics release here (PDF).
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I have been hoping for the last few years that some kind of break through will come by way of stem cell treatment for people with macular hole. Present day surgical treatment is very complicated and without any confirmed success rate. Hopefully the research carried out by ThromboGenics NV by giving microplasim injection has shown good results for treatment of vitro macular adhesion.However I have not heard any new information subsequent to the news item of 9 oct 2010.Waiting for any new information on the subject.
you are mistaken about macular hole surgery- it is often very successful and the data has been published many times in many clinical trials. of course, a simple injection would be preferable!
Would like to know where I could get MICROPLASMIN treatmente, in U.S.A.
If not,if they do it in Argentina or Costa Rica
Thanks.
R. Viquez
i believe microplasmin is available anywhere in the u.s.
Ari – Do you know where microplasmin is offered in Colorado?
no-sorry
I would also like to know where I could get MICROPLASMIN treatment, in U.S.A.i.e., Boston Massachusetts.
I have had 2 macular holes in one eye and my vision is declining again. I am told that the OCT does not show that the macular hole is reopened.
My current retina MD seems to be unaware of any new experiemental treatments and indicated that surgery is the only treatment option which I have ruled out. I wondered if I now have a macular pucker and if microplasmin treatment will also work.
I do not believe that this study and the microplasmin treatment is well known.