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Will Microplasmin Injections Transform Treatment of Vitreomacular Adhesion (Traction) and Macular Hole?

Posted By Dr. Ari Weitzner On October 9, 2010 @ 11:32 pm In Retina | Comments Disabled

Last month, ThromboGenics NV presented the results from the successful microplasmin MIVI-TRUST Phase III program at the EURETINA (European Society of Retina Specialists) Congress in Paris, France (MIVI-TRUST is short for “Microplasmin for IntraVitreous Injection-Traction Release without Surgical Treatment”).

The MIVI-TRUST program is the largest interventional clinical program ever performed to specifically evaluate the vitreoretinal interface in patients with retinal disorders, involving a total of 652 patients at 90 centers across the U.S. and Europe.

The results showed the potential of microplasmin injections to transform the treatment of a range of retinal disorders. Specifically, the Phase III program showed that microplasmin injections:

  • Were successful in resolving vitreomacular adhesion (VMA) (also known as vitreomacular traction)
  • Were able to cure full thickness macular hole (FTMH) without the need for surgery
  • Delivered an improvement in the vision of patients without the need for surgery
  • Were safe and well tolerated; there was no evidence of an increased risk of retinal tear or detachment

Read the full ThromboGenics release here [1] (PDF).


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[1] here: http://www.thrombogenics.com/html/documents/10_THR_16MicroplasminPooledResults_FINAL_EN.pdf

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