Does Microplasmin Cause Posterior Vitreous Detachment?

July 19, 2009

In this month’s Ophthalmology, a study looked at intravitreal injection of recombinant Microplasmin to induce¬†posterior¬†vitreous detachment (PVD), a useful thing to the retinal surgeons. It appears they had good success- they are working on the best dose and best timing. I would think that since a complete PVD is protective against NVD, NVE,¬† macular holes etc., that Microplasmin may very well become more routine than just as a pre-op for the retina surgeons




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3 Responses to “Does Microplasmin Cause Posterior Vitreous Detachment?”

  • ari

    it has recently been approved.

  • I wish they can find the right way/ dose/ time to use soon.
    There are some studies show benefit of microplasmin injections for many diseases, such as MH.
    I think we gonna see many more studies in the next few yrs.

  • I have long been telling patients and friends that if it weren’t for the vitreous, there would probably be NO such thing as surgical retina. There would be no retinal tears or retinal detachments. Probably no such thing as ERM’s or macular holes. Highly likely no NVE/NVD or least those leading to traction detachments. I think CME and diabetic macular edema would not exist either.

    If a posterior vitreous detachment could be induced, or, at least, everyone get a vitrectomy, now that would be something!

    There might be some neovascularization of the iris, but that might now fall under the category of glaucoma, wouldn’t it?

    Randall V. Wong, M.D.
    Retina Specialist