In this month’s Ophthalmology, a study looked at intravitreal injection of recombinant Microplasmin to induce posterior vitreous detachment (PVD), a useful thing to the retinal surgeons. It appears they had good success- they are working on the best dose and best timing. I would think that since a complete PVD is protective against NVD, NVE,  macular holes etc., that Microplasmin may very well become more routine than just as a pre-op for the retina surgeons