Study on Using ILARIS® to Treat Proliferative Diabetic Retinopathy

May 15, 2012

The Department of Ophthalmology at Triemli Hospital in Zurich is recruiting recipients for a study evaluating the efficacy and safety of Canakinumab (ILARIS®) to treat proliferative diabetic retinopathy secondary to type 1 and 2 diabetes.

Ten subjects will be enrolled to receive 150 mg Canakinumab (ILARIS®) by subcutaneous injection. Beginning on day 0, each subject will receive a subcutaneous injection of study drug every 8 weeks for 16 weeks, a total of 3 injections. All subjects will undergo regular follow-up assessments every 8 weeks through 24 weeks. Fluorescein angiography (FA) will be repeated every 8 weeks. The primary outcome being sought is the regression of retinal neovascularizations by week 24.

Key secondary outcomes sought include regression of diabetic macular edema, and change in best-corrected visual acuity.

Click here to learn more about this study.




Jump down to form below to submit your own comments

Trackback URL

Have insights to contribute? Please submit your comment below