Is Descemet’s Stripping Endothelial Keratoplasty (DSEK) Effective For Treating Fuchs Endothelial Dystrophy?
March 1, 2009
Surgery for corneal endothelial dysfunction has been moving away from penetrating keratoplasty in favor of posterior lamellar keratoplasty techniques, in which only selected tissues are grafted. A technique rapidly gaining popularity is endothelial keratoplasty with stripping of Descemet’s membrane, in which the host tissue is replaced by the membrane and endothelium — and a thin slice of cornea — from the donor eye.
The addition of the new tissue creates an interface that can scatter light and interfere with vision. As reported by MedPage Today, a study published in the February 2009 issue of Archives of Ophthalmology led by Dr. Sanjy Patel of the Department of Ophthalmology at the Mayo Clinic in Rochester Minnesota, suggests that the retained host cornea itself also undergoes changes that continue to reduce visual acuity, even six months after the procedure was completed when swelling in the cornea has resolved.
Read more about the study and its outcomes on the MedPage Today website, including a short audio presentation by Dr. Patel. An abstract of the published study in the Archives of Ophthalmology website, entitled “The Effect of Corneal Light Scatter on Vision After Descemet Stripping With Endothelial Keratoplasty,” is available here.
We invite readers to submit comments below regarding their own experiences using PKP vs. DSEK vs. DLEK for treatment of Fuchs’ Dystrophy and pseudophakic bullous keratopathy.
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