Is Valtrex Helpful in Treatment of Acute Zonal Occult Outer Retinopathy?

October 23, 2010

A small study in AJO demonstrated a nice response to Valtrex in these AZOOR patients. This suggests that the Herpes virus is indeed the culprit. Although AZOOR is rare, a larger, prospective study might be nice.

 

 

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9 Responses to “Is Valtrex Helpful in Treatment of Acute Zonal Occult Outer Retinopathy?”

  1. Jane on June 23rd, 2011 11:01 am

    I took Valtrex after having AZOOR for 9 years. I have seen no change at all.

  2. Dr. Ari Weitzner on June 26th, 2011 11:04 am

    if valtrex is started after the damage is done, we would not expect any change- so it depends on when it was started.

  3. Tonya on June 28th, 2011 7:55 pm

    If there is a study out there, I would volunteer, I was recently diagnosed with AZOOR and would love to regain my vision…even if it is a small amount

  4. ari weitzner on June 29th, 2011 1:20 pm

    im afraid vision cannot be restored after azoor has taken its toll–it causes too much damage and scarring. i think the best we can do is limit the damage.

  5. Nicole on July 22nd, 2011 8:56 am

    Hi Dr. –
    Can you tell me what the nice response was? Was it their vision loss was limited, was sight regained, did their flashing lights stop? Just curious as to how it was found responsive.

    I just started the Valtrex yesterday for my AZOOR.

  6. Dr. Ari Weitzner on July 24th, 2011 12:47 pm

    improvement in vision (even back to 20/20) and improvement in visual field loss.

  7. Cathie Eaton on October 5th, 2011 9:11 am

    I was diagnosed with AZOOR in June of 2001 after doctors searched six months for the cause of my visual field loss. I have been taking Valtrex for oral herpes for many years. I have not had any improvement in my symptoms—nor have they worsened. If there is a study I, too, would volunteer. I know my sight will not be returned, but I would like to help others not loose so much of theirs.

  8. ari on October 6th, 2011 1:46 pm

    valtrex is the only treatment i am aware of.

  9. Cherry on October 14th, 2011 10:33 am

    I was misdiagnosed with retinitis pigmentosa over a year ago. Tried eyedrops (can’t remember the name) and Diamox sequels (500mg bid) with no improvement. Just yesterday saw another retina specialist who diagnosed AZOOR. I am on steroid treatment, 30-day oral and 3 ocular injections at 60-day intervals, in addition to 6-12 months of immuno-supporession therapy.

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