Can Kenalog Before Panretinal Photocoagulation Protect Against Visual Loss and Macular Thickening?

June 11, 2009

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Dr. Ari Weitzner

Researchers randomized 41 patients with bilateral severe nonproliferative diabetic retinopathy or proliferative diabetic retinopathy to a single posterior sub-Tenon capsule injection of Kenalog in one eye and no injection in the contralateral eye before panretinal photocoagulation. From baseline to six months, there was statistically significantly less change in logMAR BCVA and foveal thickness in the treatment group than in the control group. The authors conclude that the triamcinolone prevents PRP-induced macular thickening, and thereby results in less visual loss. British Journal of Ophthalmology, June 2009.

 

 

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2 Responses to “Can Kenalog Before Panretinal Photocoagulation Protect Against Visual Loss and Macular Thickening?”

  1. Randall V. Wong, M.D. on June 17th, 2009 8:18 pm

    I think most of us forget that controlling macular edema, first, with focal photocoagulation prevents additional macular edema after panretinal photocoagulation. However, when those studies were introduced, we had no way of determining macular thickness.

    Remember economics? Apples vs. Oranges?

    Randall V. Wong, M.D.
    Retina Specialist
    http://www.TotalRetina.com

  2. Dr. Weitzner on June 18th, 2009 7:37 pm

    of course you’re right- we were always told to do focal firsy before proceeding with prp. but maybe the kenalog improves the situation even more…

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