The results of a randomized clinical trial, published in the Archives of Ophthalmology, detected no changes in visual function or intraocular pressure, or signs of retina damage, after the daily use for 6 months of sildenafil (Viagra) or tadalafil (Cialis).

In the study, healthy men with or without mild erectile dysfunction, between 30 and 65 years old and with no ophthalmologic abnormalities or risk factors, were randomly assigned to daily treatment with Viagra 50 mg, Cialis 5 mg, or placebo. The analysis included 155 men who completed 6 months of treatment and 212 men who completed 3 months.

As reported by MedPage Today, neither active treatment group differed significantly from placebo with respect to the primary endpoint of mean change in electroretinography (ERG) b-wave amplitude in both eyes. Most other ERG variables, including visual function, intraocular pressure, and anatomic assessments also did not differ among the groups.

Read ^[1] a more detailed description of the study and findings on MedPage Today.