Glaucoma Today: A new syndrome has been identified, and just like Flomax-related floppy-iris syndrome, it’s something I have notice myself in hindsight. Patients taking prostaglandins (Xalatan, Travatan, Lumigan) can sometimes develop deepening of the upper eye lid sulcus, ptosis, periorbital fat atrophy and retraction of the lower lids. They look a  little like those with scleroderma. Let’s keep an eye out for this side effect, as it is cosmetically significant.