OSN: Several promising treatments are in the pipeline for dry eye, which is an “epidemic” and can drive patients to drink. Secretagogues stimulate the eye to produce its own tears, like Restasis. One is called Lancovutide which was originally used in cystic fibrosis. Rebamipide’s mechanism is to increase the mucin level in tears, which makes the tears more stable and less prone to evaporate. A company called Mimetogen is promoting a nerve growth factor (MIM-D3) which nurtures the corneal nerves which stimulate the reflex responsible for tearing.