I read in a throwaway that researchers now have a gizmo that can image the retinal pigment epithelium (RPE) in vivo. It’s called adaptive optics autofluorescent imaging. They were able to demonstrate changes in the RPE after exposure to high intensity light. I continue to be stunned by the progress in imaging- some of those high definition  OCT scans look just like a histology slide. I wouldn’t be surprised if 25 years from now, looking into the eye with the indirect using a 90 diopter lens will seem quaint.