Comments on: Stemedica Cell Technologies Announces Breakthrough Discovery in Use of Stem Cells for Treating Retinal Degeneration http://eyedocnews.com/001557-stemedica-cell-technologies-announces-breakthrough-discovery-in-use-of-stem-cells-for-treating-retinal-degeneration/ Ophthalmology on the Web Mon, 21 May 2012 18:33:03 +0000 hourly 1 http://wordpress.org/?v=3.3.2 By: ari http://eyedocnews.com/001557-stemedica-cell-technologies-announces-breakthrough-discovery-in-use-of-stem-cells-for-treating-retinal-degeneration/comment-page-1/#comment-4183 ari Sun, 04 Sep 2011 01:31:01 +0000 http://eyedocnews.com/?p=1557#comment-4183 once the retina dies from crao, it cannot be restored. we are very far away from restoring dead nervous tissue. hopefully, in the next couple of generations, stem cells will help. the great focus now is on the spinal cord, not the retina, but any research there will be applicable. once the retina dies from crao, it cannot be restored. we are very far away from restoring dead nervous tissue. hopefully, in the next couple of generations, stem cells will help. the great focus now is on the spinal cord, not the retina, but any research there will be applicable.

]]> By: Elise Leval http://eyedocnews.com/001557-stemedica-cell-technologies-announces-breakthrough-discovery-in-use-of-stem-cells-for-treating-retinal-degeneration/comment-page-1/#comment-4177 Elise Leval Sat, 03 Sep 2011 12:42:50 +0000 http://eyedocnews.com/?p=1557#comment-4177 Will someone please start a blog of the possibility of reversing blindness caused by CRAO (Central Retinal Artery Occlusion)? Is this subject too sensitive for discussion, and /or have researchers given up? Are CRAO victims condemned to a liftime of blindness? Will someone please start a blog of the possibility of reversing blindness caused by CRAO (Central Retinal Artery Occlusion)? Is this subject too sensitive for discussion, and /or have researchers given up? Are CRAO victims condemned to a liftime of blindness?

]]> By: Dr K James http://eyedocnews.com/001557-stemedica-cell-technologies-announces-breakthrough-discovery-in-use-of-stem-cells-for-treating-retinal-degeneration/comment-page-1/#comment-382 Dr K James Mon, 13 Jul 2009 23:16:57 +0000 http://eyedocnews.com/?p=1557#comment-382 Greetings everyone, Nice work with the RPE cells. I can't see RPE cells logically being the answer since they must be taken from a source, UNLESS of course, you can multiply them in large quantities for recipients. Then of course, they may be well suited for the job.. The result seems good in thickening the retina, however, is the thickness a stable thickness which will prevent CNV? I sent Xcell a mail about this in Germany, and have had no reply although I've contacted them several times within 6 months. The reason I say this, is because they treated an AMD patient, which they advertise on their site and show a photograph with scarring decreases after treatment. however, they mentioned nothing on improvements in acuity, which is what most people would be looking for. From a marketing standpoint, any improvement would have been world news, so I guess the lack of response, answers my query.. From a clinical perspective, strengthening the RPE and retina in general, is beneficial in terms of preventing advancement of MD, etc., for that condition and others. I would be interested if anyone could keep me updated,and of course, I will do the same. I have this sneaking suspicion that, for successful retinal treatment with stem cells, the patient will have to undergo multiple treatments, involving doses per unit time. The reason is, even in utero, the process is a slow framework building style, with hormone inducement for differentation and specialization of progenitor cells. This will probably be the same in the patient undergoing treatment, UNLESS, they can harvest the retina under sterile lab conditions and then transplant. I have a feeling, both ways will evolve and for different degrees of damage suffered by the patient in regards to their condition.. In any event, "hats off" to those of you trying to progress this research.. I used to do a little recombinant dna work before I became a doc, and it is an exciting area, I wish I was in now... I have some inducement ideas for stem cells, but it's a grey area.. Oh well, maybe someday I'll have my own laboratory, on my own island, with my own laws. Until then, the way forward is to humanely conduct controlled stem cell trials.. THE KEY IS TO KEEP TREATMENT COSTS DOWN SINCE THE PATIENT HAS TO PAY AT THIS POINT IN TIME. If costs are kept to a minimum, then patients can undergo multiple stem cell implants, which may be the way forward... Qoote me on that, if you will and God bless all.. Dr Ken James Greetings everyone,
Nice work with the RPE cells. I can’t see RPE cells logically being the answer since they must be taken from a source, UNLESS of course, you can multiply them in large quantities for recipients. Then of course, they may be well suited for the job.. The result seems good in thickening the retina, however, is the thickness a stable thickness which will prevent CNV? I sent Xcell a mail about this in Germany, and have had no reply although I’ve contacted them several times within 6 months. The reason I say this, is because they treated an AMD patient, which they advertise on their site and show a photograph with scarring decreases after treatment. however, they mentioned nothing on improvements in acuity, which is what most people would be looking for. From a marketing standpoint, any improvement would have been world news, so I guess the lack of response, answers my query..
From a clinical perspective, strengthening the RPE and retina in general, is beneficial in terms of preventing advancement of MD, etc., for that condition and others. I would be interested if anyone could keep me updated,and of course, I will do the same.
I have this sneaking suspicion that, for successful retinal treatment with stem cells, the patient will have to undergo multiple treatments, involving doses per unit time. The reason is, even in utero, the process is a slow framework building style, with hormone inducement for differentation and specialization of progenitor cells. This will probably be the same in the patient undergoing treatment, UNLESS, they can harvest the retina under sterile lab conditions and then transplant. I have a feeling, both ways will evolve and for different degrees of damage suffered by the patient in regards to their condition..
In any event, “hats off” to those of you trying to progress this research.. I used to do a little recombinant dna work before I became a doc, and it is an exciting area, I wish I was in now… I have some inducement ideas for stem cells, but it’s a grey area..
Oh well, maybe someday I’ll have my own laboratory, on my own island, with my own laws. Until then, the way forward is to humanely conduct controlled stem cell trials.. THE KEY IS TO KEEP TREATMENT COSTS DOWN SINCE THE PATIENT HAS TO PAY AT THIS POINT IN TIME. If costs are kept to a minimum, then patients can undergo multiple stem cell implants, which may be the way forward… Qoote me on that, if you will and God bless all..
Dr Ken James

]]> By: Irv Arons http://eyedocnews.com/001557-stemedica-cell-technologies-announces-breakthrough-discovery-in-use-of-stem-cells-for-treating-retinal-degeneration/comment-page-1/#comment-331 Irv Arons Thu, 02 Jul 2009 02:42:33 +0000 http://eyedocnews.com/?p=1557#comment-331 According to my contact within the company, this study was done with just stem cells. A combination study, using a laser to impact the retina and/or RPE cells, followed by application of stem cells will be started shortly. For more on Stemedica and what they are doing, please see my writeup on AMD therapies: AMD Update 5: Emerging Technologies for Treating AMD link: http://irvaronsjournal.blogspot.com/2009/04/amd-update-5-emerging-technologies-for.html Irv Arons According to my contact within the company, this study was done with just stem cells. A combination study, using a laser to impact the retina and/or RPE cells, followed by application of stem cells will be started shortly.

For more on Stemedica and what they are doing, please see my writeup on AMD therapies: AMD Update 5: Emerging Technologies for Treating AMD

link: http://irvaronsjournal.blogspot.com/2009/04/amd-update-5-emerging-technologies-for.html

Irv Arons

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